Featured Nanostructured Frameworks & MOF Grades
Standard and custom metal-organic framework powders available for immediate evaluation sampling and ton-scale commercial procurement.
Understanding MIL-100 MOF Architecture & Crystalline Mechanics
An in-depth chemical breakdown of Materials Institute Lavoisier #100: Mesoporous Cages, Lewis Acid Active Sites, and Thermal Hydro-Stability.
Hierarchical Dual-Cage Structure
MIL-100 features a zeotype architecture containing two distinct types of mesoporous cages: smaller cages of ~25 Å internal diameter (accessed via 5.5 Å pentagonal windows) and larger cages of ~29 Å internal diameter (accessed via 8.6 Å hexagonal windows).
Coordinatively Unsaturated Metal Sites
Upon thermal activation, terminal water molecules bound to the M3O trimers are removed, generating a dense concentration of open Lewis acid sites. These active sites provide extraordinary catalytic activity and selective chemisorption towards polar gas molecules.
Unmatched Hydrothermal Stability
Unlike traditional copper or zinc-based MOFs (e.g., HKUST-1, MOF-5) which collapse in humid environments, trivalent iron and aluminium MIL-100 frameworks maintain structural integrity even after prolonged exposure to boiling water and corrosive acidic aqueous solutions.
MIL-100 Variant Technical Specification Matrix
| Parameter / Metric | MIL-100(Fe) | MIL-100(Al) | MIL-100(Cr) |
|---|---|---|---|
| Metal Center (Node) | Iron (Fe³⁺) | Aluminium (Al³⁺) | Chromium (Cr³⁺) |
| Organic Linker | Trimesic Acid (BTC) | Trimesic Acid (BTC) | Trimesic Acid (BTC) |
| BET Surface Area (m²/g) | 1,800 – 2,200 | 1,900 – 2,400 | 2,000 – 2,400 |
| Pore Volume (cm³/g) | 0.90 – 1.10 | 0.95 – 1.15 | 1.00 – 1.20 |
| Thermal Stability (°C in Air) | Up to 300 °C | Up to 350 °C | Up to 380 °C |
| Aqueous Hydro-Stability | Excellent (pH 1 - 9) | Exceptional (pH 2 - 10) | Outstanding (pH 0 - 11) |
| Primary Application Focus | Biomedical, Water Remediation, CO₂ Capture | Dehumidification, Catalysis, Gas Separation | Industrial Catalysis, High-Temp Adsorption |
Information Gain Insight: Selecting between MIL-100 variants requires balancing hydrothermal robustness with eco-toxicity and processing cost. While MIL-100(Cr) delivers highest thermal stability, regulatory requirements under REACH favor MIL-100(Fe) and MIL-100(Al) for large-scale environmental and HVAC integration due to their benign, non-toxic metal foundations.
Industrial Manufacturing & China Factory Production Scale
Bridging the lab-to-market gap: How advanced Chinese chemical engineering enables ton-scale MOF supply with unmatched cost efficiencies and lot-to-lot consistency.
Solvent-Free & Water-Based Eco-Synthesis
Historically, MOF synthesis relied on high volumes of expensive, toxic organic solvents like N,N-dimethylformamide (DMF). Our advanced production lines utilize aqueous hydrothermal and continuous mechanochemical reactive crystallization. This green synthesis route eliminates solvent waste, reduces precursor costs by up to 60%, and complies with global carbon-neutral manufacturing mandates.
Integrated Upstream Supply Chain
Operating within China's mature chemical industrial clusters provides direct access to high-purity inorganic salts (Iron/Aluminium nitrates and chlorides) and primary organic linkers (Trimesic Acid/BTC). By securing raw material pipelines at the source, our manufacturing facility insulates global buyers from international supply chain bottlenecks and volatile price fluctuations.
Macro-Industry Solutions & Global Decarbonization Pathways
Engineered pore architectures solving critical challenges across clean energy, environmental remediation, industrial gas processing, and HVAC energy conservation.
CO₂ Capture & Flue Gas Separation
With ultra-high micropore volume and accessible iron/aluminium open metal sites, MIL-100 exhibits superior affinity for carbon dioxide over nitrogen and methane. In industrial post-combustion carbon capture systems, MIL-100 lowers regeneration temperature requirements from 120°C (amine scrubbing) to below 70°C, drastically reducing parasitic thermal energy losses.
Desiccant Cooling & Atmospheric Water Harvesting
MIL-100(Al) displays a characteristic sigmoidal (S-shaped) water sorption isotherm with steep uptake at relative humidity (RH) levels between 20% and 40%. This precise thermodynamic window allows HVAC desiccant wheels and off-grid water generators to harvest moisture under low-humidity conditions and desorb water using low-grade solar thermal energy.
Lewis Acid Catalysis & Chemical Upgrading
The coordinatively unsaturated metal sites within MIL-100(Fe) serve as strong solid Lewis acid catalysts. Industrial chemical processes utilize MIL-100 for esterification, Friedel-Crafts alkylations, sulfide oxidation, and biomass conversion (e.g., converting cellulose to platform chemicals) without the corrosion and environmental hazards of liquid acids.
Localized Application Scenarios & Engineering Benchmarks
Translating crystalline porous physics into measurable operational gains across key industrial operations.
Semiconductor Cleanroom VOC Capture
In microelectronics fabrication facilities, airborne molecular contamination (AMC) by volatile organic compounds (VOCs) causes severe silicon wafer defects. Standard activated carbon filters struggle with low-concentration trace organics. MIL-100(Fe) beds exhibit a 4.5x higher breakthrough capacity for polar VOCs (such as isopropyl alcohol, acetone, and siloxanes) at sub-ppm levels, extending cleanroom filter lifespan significantly.
Wastewater Heavy Metal Decontamination
Electroplating and mining effluent streams contain toxic heavy metal ions (Cr(VI), Pb(II), As(III)). By functionalizing the internal cages of MIL-100(Fe) with amino or thiol groups, our custom adsorbents achieve capture efficiencies over 99.8% with ultra-fast adsorption kinetics (< 15 minutes to equilibrium), reducing heavy metal concentrations far below international drinking water discharge limits.
Technical Validation Note: All MIL-100 products undergo rigorous thermogravimetric analysis (TGA) and nitrogen physisorption testing. Batch Certificates of Analysis (CoA) document BET surface area, micro/mesopore size distribution, moisture content (<2.0%), and heavy metal residue thresholds.
Global Procurement, Quality Assurance & Export Compliance
Addressing the rigorous requirements of international supply chain directors, chemical sourcing managers, and regulatory compliance teams.
Batch Quality Control & CoA Integrity
Every shipment includes lot-specific PXRD spectra verifying crystalline phase purity, BET surface area plots, laser diffraction particle size distribution (PSD), and ICP-OES metal assay reports. We guarantee zero phase contamination from unreacted organic linkers or amorphous metal oxides.
Export Packaging & Moisture Barriers
To prevent premature ambient moisture saturation during transit, MIL-100 powders are vacuum-sealed under dry argon in multi-layer aluminum foil pouches (1kg, 5kg) or packaged in UN-certified fiber drums (25kg, 50kg) equipped with double PE liners and desiccant sleeves.
Regulatory Compliance & Logistics
Fully compliant with REACH regulations (EU), TSCA inventory mandates (USA), and GHS classification standards. We provide comprehensive Safety Data Sheets (SDS) in 12 languages and support DDP, FOB, and CIF maritime and air cargo logistics under HS Code 3824.99.
Industrial MOF Roadmap: 2025–2030 Technology Trends
How continuous manufacturing, structural shaping, and AI-driven ligand engineering are shaping the next decade of porous nanomaterials.
1. Transition from Loose Powders to Engineered Bodies
While early MOF commercialization focused on fine synthesized powders, industrial applications demand shaped structures to minimize pressure drop in continuous flow reactors. Leading suppliers are introducing extrudates, microspheres, ceramic foam coatings, and binder-free monoliths that preserve >90% of intrinsic BET surface area while eliminating airborne dusting hazards.
2. Machine Learning & Automated Screening
Integration of high-throughput computational chemistry and machine learning algorithms allows rapid screening of metal-linker combinations. By predicting adsorption isotherms for complex gas mixtures prior to laboratory synthesis, custom MIL-100 derivatives can be tailored for specific industrial waste streams in weeks rather than years.
Explore Complete MOF & Advanced Porous Material Catalog
Complementary framework powders, specialized adsorbents, and tailored pore solutions for industrial research and bulk commercial deployment.
Frequently Asked Questions (Technical & Procurement FAQ)
Expert technical answers regarding MIL-100 MOF handling, custom synthesis, volume pricing, and evaluation samples.
What is the key difference between MIL-100(Fe) and MIL-100(Al)?
While both share identical zeotype dual-cage crystal structures and trimesate organic linkers, MIL-100(Fe) features iron nodes which provide exceptional biocompatibility, lower cost, and high Lewis acidity ideal for catalytic reactions and aqueous pollutant removal. MIL-100(Al) utilizes light aluminium centers, offering slightly higher BET surface area (~2,200 m²/g vs 1,900 m²/g), lower density, and optimal performance in atmospheric water harvesting and HVAC desiccant applications.
Can you supply evaluation samples for lab-scale feasibility testing?
Yes. Qualified corporate R&D laboratories and research institutions can request 1g to 5g evaluation sample kits accompanied by complete characterization data (PXRD, N₂ isotherm, TGA). Sample dispatch typically occurs within 3 to 5 business days via global express shipping.
How should MIL-100 powders be stored to prevent loss of surface area?
Although MIL-100 exhibits remarkable hydrothermal stability compared to standard MOFs, exposed powders will naturally adsorb ambient atmospheric moisture over time. We recommend storing material in sealed containers under dry nitrogen or vacuum. Prior to application testing, heat-activate the powder at 130°C – 150°C under vacuum for 6 to 12 hours to vacate open metal sites.
What product forms and custom particle sizes are available?
Standard MIL-100 is supplied as a fine dry crystalline powder (average d50 particle size of 1 µm to 5 µm). Upon request, we provide liquid dispersions (in water, ethanol, or organic solvents), nano-sized particles (d50 < 200 nm), and shaped bodies including extruded pellets, granules, and coated substrate foams.
What are your typical minimum order quantities (MOQ) and lead times for bulk orders?
Standard catalog quantities begin at 100g for research orders. Commercial pilot MOQs start at 5 kg, while commercial contract orders can scale to multi-ton shipments. Standard lead time for ton-scale production is 3 to 4 weeks from order confirmation.
Partner with a Premier MIL-100 MOF Manufacturer
Connect directly with our chemical engineering team to request technical datasheets, discuss OEM/ODM custom synthesis, or obtain batch quote pricing.
Request Technical Consultation & Quote