Featured MOF Portfolio
High-Purity Metal-Organic Framework Powders & Dispersions
Explore our export-grade MOF products optimized for gas separation, carbon capture, water harvesting, and catalytic degradation.
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Best China Suppliers Factory MIL-88A(Fe) Powder Metal Organic Frameworks for Environmental Remediation
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Section 1.0 — Crystallography & Molecular Mechanics
Chemical Architecture & Structural Breathing Dynamics of MIL-88A(Fe)
MIL-88A(Fe), chemically denoted as $[Fe_3O(O_2C-CH=CH-CO_2)_3(H_2O)_2X]$ (where $X = Cl^-$ or $OH^-$), belongs to the prestigious Material of Institut Lavoisier (MIL) class of carboxylate-based porous coordination polymers. Synthesized from iron(III) metal centers and non-toxic, eco-friendly fumaric acid linkers, MIL-88A(Fe) exhibits a three-dimensional open-framework constructed from iron trimers featuring central oxo-centered trimeric units $[Fe_3(\mu_3-O)(O_2C-)_6]$. This specific iron-oxygen cluster geometry creates a robust, highly stable framework that operates as a premier heterogeneous photo-Fenton catalyst and selective adsorbent for global industrial applications.
Unlike rigid metal-organic framework structures such as MOF-5 or HKUST-1, MIL-88A(Fe) is world-renowned for its remarkable "breathing effect" (flexible swelling and shrinking lattice behavior). Upon guest molecule adsorption or solvent intercalation (such as water, ethanol, or polar organic solvents), the unit cell volume of MIL-88A(Fe) can undergo reversible structural expansion exceeding 85% without sacrificing its crystalline framework integrity. This dynamic structural adaptability provides superior guest-host interactions, allowing selectively targeted molecules to diffuse efficiently through its flexible channels while preventing permanent pore collapse during harsh industrial wetting and drying cycles.
Key Insight for Process Engineers: The breathing phenomenon of MIL-88A(Fe) allows it to maintain exceptional structural endurance during repeated hydration-dehydration cycles. This prevents the mechanical pulverization commonly observed in rigid MOFs, drastically lowering filtration pressure drops in continuous flow reactors.
Physicochemical Specifications & Material Metrics
To support global procurement teams and industrial chemical designers, our factory-direct MIL-88A(Fe) is manufactured under rigid digital quality control protocols. Below is a comprehensive specification breakdown detailing the benchmark chemical parameters of our export-grade powder:
| Physicochemical Parameter | Standard Commercial Grade | Ultra-Pure Catalytic Grade | Analytical Characterization Technique |
|---|---|---|---|
| Chemical Formula | $Fe_3O(C_4H_2O_4)_3(OH)\cdot nH_2O$ | $Fe_3O(C_4H_2O_4)_3(OH)\cdot nH_2O$ | Elemental Analysis & FTIR spectroscopy |
| CAS Registry Number | 1374976-55-4 | 1374976-55-4 | Official Regulatory Index |
| BET Surface Area | $\ge 650 \text{ m}^2/\text{g}$ (Dry state) | $\ge 950 \text{ m}^2/\text{g}$ (Hydrated/Swollen state) | $N_2$ Adsorption Isotherms at 77 K |
| Pore Volume | $0.35 - 0.50 \text{ cm}^3/\text{g}$ | $0.55 - 0.72 \text{ cm}^3/\text{g}$ | Density Functional Theory (DFT) Model |
| Average Crystallite Size | $200 \text{ nm} - 800 \text{ nm}$ | $50 \text{ nm} - 150 \text{ nm}$ (Nano-spindle) | High-Resolution FE-SEM & TEM |
| Thermal Stability Window | Stable up to $280^\circ\text{C}$ in air | Stable up to $310^\circ\text{C}$ under $N_2$ purge | Thermogravimetric Analysis (TGA) |
| Hydrothermal pH Range | pH 2.5 to pH 9.0 | pH 2.0 to pH 9.5 | Long-term aqueous leaching tests (ICP-OES) |
Section 2.0 — Industrial Execution Scenarios
Heterogeneous Catalysis, Water Remediation & Biomedical Systems
Heterogeneous Photo-Fenton Oxidation
MIL-88A(Fe) functions as an exceptional photo-Fenton catalyst under visible light illumination. The iron oxide trimers exhibit rapid photo-generated electron transfers ($Fe^{III} \to Fe^{II}$), generating hydroxyl radicals ($^\bullet OH$) and superoxide radicals ($O_2^{\bullet-}$) that rapidly mineralize persistent organic pollutants (POPs), refractory dyes, and pharmaceuticals without iron sludge accumulation.
Heavy Metal Ion Capture ($Cr^{VI}, Pb^{2+}, As^{V}$)
Owing to its uncoordinated oxygen sites and surface carboxyl functional groups, MIL-88A(Fe) acts as a highly selective adsorbent for toxic heavy metals. It efficiently reduces toxic hexavalent chromium ($Cr^{VI}$) to less toxic trivalent chromium ($Cr^{III}$) under solar light while simultaneously immobilizing heavy metal ions inside its open pore networks.
Targeted Biomedical Drug Delivery
Composed of biocompatible iron nodes and naturally occurring fumaric acid, MIL-88A(Fe) possesses ultra-low cytotoxicity ($IC_{50} > 500 \ \mu g/mL$). It serves as a smart nanocarrier for anti-cancer therapeutics (such as Doxorubicin and 5-Fluorouracil), releasing cargo in response to acidic tumor microenvironments (pH-triggered release).
Industrial Gas Separation & VOC Removal
The breathing pore channels of MIL-88A(Fe) enable high-selectivity separation of carbon dioxide from methane ($CO_2/CH_4$) and nitrogen ($CO_2/N_2$) streams. Furthermore, its surface chemistry promotes the capture and catalytic degradation of volatile organic compounds (VOCs) such as benzene, toluene, and formaldehyde.
Solar Thermal Energy & Water Harvesting
MIL-88A(Fe) exhibits a steep S-shaped water vapor sorption isotherm under moderate relative humidity ($RH = 30\%-60\%$). Combined with low thermal regeneration temperatures ($< 70^\circ\text{C}$), it is extensively integrated into desiccant wheels and atmospheric water harvesting (AWH) prototype systems.
Section 3.0 — Manufacturing & Supply Chain Integration
China Supply Chain Dominance: Green Scale-Up & Cost Engineering
Historically, commercial deployment of Metal-Organic Frameworks was hindered by high synthesis costs, reliance on toxic organic solvents (such as $N,N$-dimethylformamide or DMF), and low batch yield. As China’s premier industrial MOF manufacturer, our facility has overcome these barriers through advanced green mechanochemical synthesis and continuous hydrothermal flow synthesis (CHFS).
Our strategically located production hub in Guangdong leverages direct upstream integration with world-class Chinese chemical suppliers. By sourcing high-purity ferric chloride ($FeCl_3\cdot 6H_2O$) and bio-based fumaric acid directly in multi-ton quantities, we eliminate supply chain volatility and reduce raw material procurement costs by up to 45% compared to Western manufacturers.
Green Solvent-Free Mechanochemistry
Our patented solid-state milling technology eliminates hazardous organic solvents during framework assembly. This green chemistry route yields over 98% mass conversion while reducing solvent recovery expenditure by 80%.
Continuous Flow Hydrothermal Scale-Up
Utilizing high-pressure continuous flow hydrothermal reactors, our production lines achieve a daily yield capacity exceeding 1.5 metric tons of MIL-88A(Fe) powder with single-digit batch variance ($CV < 2.5\%$).
Comprehensive Digital Quality Auditing
Every commercial batch is accompanied by full analytical verification, including Powder X-Ray Diffraction (PXRD) patterns, nitrogen isotherms, inductively coupled plasma mass spectrometry (ICP-MS), and TGA curves.
Enterprise Trust & Production Metrics
Global Supply Leadership by the Numbers
Empowering fortune 500 chemical enterprises, water treatment plant operators, and research institutions worldwide.
500+
Metric Tons Annual Capacity
99.2%
Crystalline Phase Purity
45+
Export Destination Countries
ISO 9001
Quality Management Certified
Section 4.0 — Global Regulatory & Procurement Protocols
Local Support, REACH Compliance & Export Logistics Safeguards
Navigating cross-border chemical procurement requires strict adherence to international safety standards, customs declarations, and environmental certifications. As a leading exporter of specialized Metal-Organic Frameworks, we provide end-to-end compliance packages tailored to regional requirements in North America, the European Union, Asia-Pacific, and the Middle East.
1. EU REACH & Global Inventory Compliance
Our MIL-88A(Fe) products are fully registered under EU REACH tonnage bands, ensuring seamless, hassle-free clearance through European ports. Furthermore, our iron fumarate frameworks comply with the United States Toxic Substances Control Act (TSCA), Japanese ENCS, and Korean K-REACH safety protocols.
2. Custom Form Factor & Packaging Engineering
To support diverse downstream handling systems, we supply MIL-88A(Fe) in tailored physical configurations:
- Ultra-Fine Dry Powder: Jet-milled powders with controlled particle size distribution ($D_{50} = 200 \text{ nm}$ or $1.5 \ \mu m$).
- Extruded Pellets & Granules: Binderless or polymer-bound 2mm–5mm cylindrical pellets designed for fixed-bed adsorption towers.
- Stable Liquid Dispersions: Pre-dispersed concentrated suspensions in water, ethanol, or isopropyl alcohol with custom anti-agglomeration surfactant packages.
3. Moisture Barrier & Dangerous Goods (DG) Packaging
Although MIL-88A(Fe) is classified as non-hazardous for air and ocean freight, its breathing framework requires rigorous moisture isolation during international transit. All bulk orders are sealed in double-layer vacuum-sealed aluminum foil bags enclosed within fiber drums fitted with active desiccant packs, guaranteeing zero hydration degradation upon arrival.
Frequently Asked Questions
Industrial Procurement & Technical Q&A
Clear engineering answers regarding MIL-88A(Fe) properties, custom synthesis, sample requests, and bulk order logistics.
What is the chemical difference between MIL-88A(Fe) and MIL-101(Fe)?
While both frameworks feature iron(III) trimer nodes, their organic dicarboxylate linkers and crystal geometries differ significantly. MIL-88A(Fe) utilizes fumaric acid (a short, rigid aliphatic linker), resulting in a flexible, breathing structure ideal for responsive water harvesting, dynamic guest adsorption, and photo-Fenton reactions. In contrast, MIL-101(Fe) utilizes terephthalic acid (BDC), yielding a rigid mesoporous framework with larger cage sizes ($29-34 \text{ \AA}$) suited for bulky drug molecule loading and macro-particle adsorption.
Can MIL-88A(Fe) be modified with functional groups like amine (-NH2)?
Yes. Our OEM custom laboratory offering includes pre-functionalized variants such as $NH_2\text{-MIL-88A(Fe)}$, synthesized using amino-fumaric acid derivatives. The inclusion of amine groups shifts the optical absorption spectrum further into the visible range ($\lambda > 450 \text{ nm}$), enhancing photocatalytic efficiency under natural sunlight while increasing selectivity for polar gases such as $CO_2$.
What evaluation sample sizes are available for commercial validation?
We provide complimentary sample kits ranging from 1g to 5g for qualified enterprise R&D departments and institutional laboratories. For pilot-plant validation trials, custom 1kg to 25kg evaluation batches can be dispatched with full batch Certificate of Analysis (COA) documents within 3 business days.
How should MIL-88A(Fe) powder be stored to maintain long-term reactivity?
MIL-88A(Fe) powder should be stored in a cool, dry environment ($15^\circ\text{C}-25^\circ\text{C}$) away from direct solar radiation in its original moisture-proof vacuum packaging. If exposed to ambient moisture prior to use, the material can be reactivated by vacuum drying at $100^\circ\text{C}-120^\circ\text{C}$ for 4 to 6 hours.
What is the typical production lead time for metric-ton procurement?
Standard off-the-shelf powder grades are maintained in continuous inventory (up to 5 metric tons ready-to-ship). For customized particle sizing or pelletized orders exceeding 10 tons, our factory lead time is typically 14 to 21 calendar days from purchase order confirmation.
Featured MOF Portfolio (Part II)
Expanded Industrial Frameworks & Catalytic Solutions
Complete your material selection with our specialized series of advanced MOF powders for gas separation, olefin recovery, and water treatment.
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