Featured MOF Products & Framework Grades
Explore our certified portfolio of Metal-Organic Framework powders, engineered for ultra-high adsorption, targeted gas separation, and environmental remediation.
Technical Whitepaper: Industrial Engineering of MIL-101(Fe) Frameworks
Metal-Organic Frameworks (MOFs), specifically MIL-101(Fe) (Matériaux de l'Institut Lavoisier No. 101, Iron-based), represent a class of highly crystalline, porous hybrid coordination polymers. Composed of iron(III) octahedral clusters interconnected by 1,4-benzenedicarboxylate (BDC) linkers, MIL-101(Fe) is engineered to deliver unprecedented internal surface area, hierarchical mesoporous windows, and environmentally benign catalytic performance.
As premier MIL-101(Fe) suppliers and exporters, our manufacturing architecture resolves historical limitations in MOF synthesis—transitioning from lab-scale solvothermal small batches to industrial-scale continuous aqueous routes. MIL-101(Fe) possesses two types of mesoporous cages (approximately 2.9 nm and 3.4 nm in diameter) accessible through microporous pentagonal and hexagonal windows (1.2 nm and 1.6 nm). This hierarchical pore structure provides exceptionally high pore volumes (up to 2.0 cm³/g) and BET specific surface areas consistently exceeding 2,800 to 3,400 m²/g.
High Surface Area & Porosity
Hierarchical mesopores (2.9–3.4 nm) engineered for rapid mass transfer, high gas storage capacity, and bulky guest-molecule encapsulation.
Heterogeneous Fenton-Like Catalysis
Rich Coordinatively Unsaturated Sites (CUS) iron sites accelerate Fe(III)/Fe(II) redox cycling for Advanced Oxidation Processes (AOPs).
Non-Toxic & Biocompatible
Iron metal nodes provide an eco-friendly profile, qualifying MIL-101(Fe) for pharmaceutical carrier systems, water treatment, and food-grade packaging compliance.
Chemical Architecture & Functional Mechanics
The structural backbone of MIL-101(Fe) is synthesized via the coordination of iron trimers ($\text{Fe}_3\mu_3\text{-O}$) with terephthalate linkers ($\text{C}_8\text{H}_4\text{O}_4$). The inclusion of terminal water/fluorine ligands allows thermal activation, driving off guest molecules to create coordinatively unsaturated Lewis acid metal sites ($\text{Fe}^{3+}$). These open metal sites act as targeted electron acceptors, enabling selective chemisorption of polar gases (e.g., $\text{CO}_2$, $\text{H}_2\text{S}$) and triggering high catalytic turnover rates in photo-Fenton degradation of organic pollutants.
Comparative Performance Metrics: MIL-101(Fe) vs Industry Standards
Our factory-grade MIL-101(Fe) undergoes rigorous digital batch analysis. Below is an engineering comparison evaluating structural parameters against common industrial MOFs.
| Material Grade | Metal Center | BET Surface Area (m²/g) | Pore Volume (cm³/g) | Thermal Stability (°C) | Primary Application Vector |
|---|---|---|---|---|---|
| KARGEN MIL-101(Fe) | Iron ($\text{Fe}^{3+}$) | 2,800 – 3,400 | 1.4 – 2.0 | Up to 320°C | Fenton Catalysts, PFAS Removal, Drug Delivery |
| MIL-100(Fe) | Iron ($\text{Fe}^{3+}$) | 1,800 – 2,200 | 0.9 – 1.1 | Up to 300°C | Wastewater Treatment, Gas Purification |
| ZIF-8 (Zinc) | Zinc ($\text{Zn}^{2+}$) | 1,300 – 1,800 | 0.6 – 0.75 | Up to 400°C | $\text{CO}_2$ Capture, Battery Separator Coatings |
| HKUST-1 (Cu-BTC) | Copper ($\text{Cu}^{2+}$) | 1,500 – 2,100 | 0.7 – 0.85 | Up to 240°C | Gas Separation, Semiconductor Gas Purifiers |
| MIL-53(Al) | Aluminium ($\text{Al}^{3+}$) | 1,100 – 1,500 | 0.55 – 0.65 | Up to 450°C | VOC Adsorption, Flexible Pore Separation |
China Factory Supply Chain Advantage: Scaling Ton-Scale Production
Historical deployment of Metal-Organic Frameworks was restricted by astronomical production costs, dependence on hazardous organic solvents (e.g., DMF, DEF), and poor batch consistency. Our modern 10,000 m² chemical manufacturing base in Guangdong, China, has pioneered green, mechanochemical, and water-based hydrothermal continuous-flow scale-up processes.
- Vertically Integrated Raw Materials: Strategic sourcing of high-purity terephthalic acid (PTA) and iron precursor salts directly from China’s leading petrochemical clusters, eliminating supply bottlenecks.
- Solvent-Free & Green Synthesis: Utilization of eco-friendly aqueous reaction systems reduced chemical waste management costs by 45%, passing economic savings directly to international procurement partners.
- Ton-Scale Annual Capacity: Dedicated pilot lines and industrial reactors capable of supplying multi-ton contracts with zero batch-to-batch structural variance.
Localization Support & Global Regulatory Compliance
Exporting sophisticated nanomaterials requires comprehensive regulatory documentation and local technical alignment. We ensure complete risk mitigation for cross-border logistics and regulatory audits.
All shipments of MIL-101(Fe) are backed by authentic laboratory certificates of analysis (CoA), Transmission Electron Microscopy (TEM) imaging, X-ray Powder Diffraction (XRD) phase purity validation, and Thermogravimetric Analysis (TGA) thermal profiles.
EU REACH & RoHS Compliance
Full compliance with EU REACH registration protocols and RoHS restrictions, enabling seamless import across North America, Europe, and Asia-Pacific markets.
Fast Customs Clearance & Freight
Expertise in dangerous goods classification (Non-DG certified options available), GHS-compliant SDS/MSDS labeling in 15+ localized languages, and IATA/IMDG air and ocean packing.
Localized Technical Assistance
Dedicated PhD-level application engineers assisting global clients with slurry formulation, surface modification, particle-size distribution tuning, and composite membrane casting.
Global Enterprise Procurement Needs & Custom Product Shaping
Procurement requirements vary greatly between academic screening, pilot testing, and full-scale industrial operations. As a customer-centric MOF manufacturer, we provide tailored supply packages ranging from 1–5 gram R&D evaluation kits to multi-ton bulk shipments.
Engineered Material Formats & Pelleted Shapes
Standard raw MIL-101(Fe) is synthesized as a fine crystalline yellow/orange powder. However, packed-bed reactors and industrial column systems suffer from massive pressure drops when loaded with unformatted powders. We overcome this bottleneck by offering custom-engineered structural shapes:
Micronized Powders
Adjustable particle size ($d_{50}$ from 200 nm up to 5 µm), customized for slurry spinning, electrospinning matrices, and battery separator coatings.
Extruded Pellets & Cylinders
Formulated using binder-free or inorganic binder systems (1.5 mm – 3.0 mm diameter) designed for high mechanical crush strength in packed gas columns.
Monoliths & Liquid Dispersions
3D honeycomb MOF ceramic monoliths for industrial exhaust air purification and stable liquid dispersions in polar/non-polar organic solvents.
Localized Application Scenarios & Industry Trends
MIL-101(Fe) is transforming environmental remediation, pharmaceutical technology, and carbon capture ecosystems.
1. Advanced Wastewater Treatment & PFAS/Pharmaceutic Removal
Due to its abundant open iron sites ($\text{Fe}^{3+}$) and stable meso-pores, MIL-101(Fe) functions as a superior photo-Fenton catalyst. Under visible light irradiation and mild $\text{H}_2\text{O}_2$ addition, it generates hydroxyl radicals ($\cdot\text{OH}$), rapidly degrading recalcitrant organic contaminants, textile dyes, per- and polyfluoroalkyl substances (PFAS), and active pharmaceutical ingredients (APIs) in municipal and industrial effluents.
2. Biogas Upgrading & Selective Gas Separation
The global energy transition demands efficient biogas scrubbing ($\text{CH}_4/\text{CO}_2$ separation) and hydrogen sulfide ($\text{H}_2\text{S}$) removal. MIL-101(Fe) exhibits preferential adsorption toward $\text{CO}_2$ over $\text{CH}_4$, providing clean biomethane streams for grid injection while operating under low desorption regeneration temperatures.
3. Biocompatible Drug Delivery & Medical Carriers
Unlike toxic chromium or lead-based MOFs, iron-based MIL-101(Fe) exhibits outstanding biocompatibility and low cytotoxicity. Its immense pore volume allows record-breaking drug payloads (e.g., loading up to 1.4 g of Ibuprofen per gram of MOF), facilitating controlled, pH-responsive drug release in targeted oncological and anti-inflammatory therapies.
4. Industry Trends: CCUS & Decarbonization Mandates
With worldwide net-zero targets driving corporate ESG initiatives, Carbon Capture, Utilization, and Storage (CCUS) technologies are shifting from liquid amine scrubbers to solid MOF adsorbents. MIL-101(Fe) offers a 40% reduction in thermal energy regeneration penalties compared to traditional monoethanolamine (MEA) solvent systems.
Frequently Asked Questions (FAQ) & Technical Guidance
While both are iron-carboxylate frameworks, MIL-101(Fe) uses terephthalic acid (BDC) as its organic linker, resulting in larger mesoporous cages (2.9 nm and 3.4 nm) and higher BET surface areas (2,800–3,400 m²/g). MIL-100(Fe) utilizes trimesic acid (BTC), producing smaller cages (2.5 nm and 2.9 nm) with a BET surface area around 1,800–2,200 m²/g. MIL-101(Fe) is generally preferred for large-molecule adsorption and maximum drug loading.
Yes, qualified commercial entities and institutional research groups engaged in active product development can request 1–5 gram evaluation samples free of charge. Freight and customs clearance fees are covered by the recipient. Contact our engineering support team with your project details to qualify.
MIL-101(Fe) exhibits robust hydrothermal stability across acidic and neutral aqueous media (pH 2 to pH 8). For long-term liquid Phase Advanced Oxidation Processes (photo-Fenton), controlling iron leaching is critical; our specialized thermal activation treatment reduces iron ion leaching rates to below 0.05 mg/L, exceeding EPA drinking water safety guidelines.
Standard R&D sample orders ship in moisture-sealed aluminum foil bags or glass vials (10g, 50g, 500g). Bulk industrial orders are packaged in 25 kg fiber drums lined with double-layer vacuum polyethylene bags. Standard lead times for stock grades are 3–5 business days; custom ton-scale OEM orders typically ship within 2–3 weeks.
Absolutely. Our PhD-led R&D team regularly synthesizes amine-functionalized variants (e.g., $\text{NH}_2\text{-MIL-101(Fe)}$) for enhanced $\text{CO}_2$ capture selectivity, as well as bimetallic Fe/Ti or Fe/Zr mixed-metal framework nodes. Custom particle size distribution, granulation, and dispersion services are fully supported under mutual Non-Disclosure Agreements (NDAs).
To achieve maximum BET surface area, we recommend degassing the material under vacuum ($< 10^{-2}$ Torr) at 120°C for 6 to 12 hours prior to adsorption or gas storage measurements. This step evacuates ambient moisture trapped within the mesoporous cages without damaging the crystal framework.
Complete Metal-Organic Framework Inventory
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